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Dermatology Diaries

Friday, August 16, 2013

PRP 's Dermal Filler Cousin - PRFM

PRP in new delhi
Areas Treated with Dermal Fillers and PRFM for Youthful Appearance

What is Platelet Rich Fibrin Matrix (PRFM)?
Platelet-rich fibrin matrix (PRFM) involves injection of the patient's own plasma containing platelets, for the treatment of wrinkles and for volume restoration. It is a modification to the Platelet Rich Plasma (PRP) known popularly as the "vampire facelift" or “Plasma facelift” and belongs to the field of regenerative medical science for the repair and rejuvenation of cellular wear and tear.

How does PRFM repair wrinkles and folds?
Platelet Rich Fibrin Matrix forms a scaffold in which new cells, blood capillaries and collagen is laid. It mimics the natural repair process of the body using the patient's natural biology to address skin defects and volume loss, triggering production of new cells and collagen and remodelling the existing matrix.

What are dermal fillers?
Currently the most popular options for wrinkle correction are Non Animal Stabilized Hyaluronic Acid (NASHA) dermal fillers such as Juvederm, Restylane and Esthelis. These are available as sterile pre-filled syringes. When injected they lift the fold by volumizing the subjacent tissues. Effects last for 6-18 months depending on the type of filler used. NASHA dermal fillers are non-allergenic, are FDA approved and have a proven safety profile.

Platelet Rich Fibrin Matrix an all natural dermal filler?
Platelet Rich Fibrin Matrix (PRFM) are now being used as wrinkle filler into the laugh lines, jowls, tear trough and cheek area by doctors who have already pioneered the PRP treatment protocols. The PRFM filler requires about 30 minutes for each treatment, similar to a Juvederm or Restylane procedure.

Results of PRFM as wrinkle filler?
The results are visible instantly with complete lifting of the fold. There is some resorption over the next 2-7 days, with gradual improvement in the injected area over the next 3-5 weeks. Final correction is expected at 6-8 weeks and can last as long as 18 months. Better results are seen with a total of 2-3 treatments given 3-4 months apart. Patients can expect to see better results as they receive more treatments. With time, the results of PRFM fillers get better and better.

Who should consider a PRFM filler treatment?
This procedure is suitable for any one who wishes to reduce volume loss, wrinkles, folds, fine lines and textural changes of the skin. It will definitely appeal to those who are looking for a natural approach to volumizing the face and treating or reducing wrinkles. Best results are achieved when PRFM fillers are started in early or mid 30’s as a preventive rather than reparative procedure.

Are there any side effects?
Because this filler is made from the patient's own blood, there is no risk for rejection, infection, or an allergic reaction.

How much does PRFM filler cost?
Cost of the Platelet Rich Fibrin Matrix procedure at my clinic is generally similar or less than that of hyaluronic dermal fillers and begins at Rs.12000 on wards per treatment depending on the extent of required treatment.

Can Platelet Rich Plasma fillers be combined with other cosmetic treatments?
This procedure can be combined with Botox injections, and laser rejuvenation, as well as facial surgery. This offers the benefit of instant results with long term regenerative effect. PRFM treatment is very promising in facial restoration.

Words of wisdom
The single most important factor for a good PRFM or PRP procedure is the processing of the patient’s blood. To ensure maximum corrective benefit, the right parameters need to be set. Results are much more dependable if the processing of the sample is done on the spot by the treating dermatologist.

Keep looking beautiful
Dr Niketa